PEEK Hplc Column

Our PEEK chromatography column hardware is designed to industry standards and can be used as a direct replacement for the original columns from the following brands, without the need for any additional adapters:

• Agilent: 1100, 1200, 1260, 1290 Infinity series.
• Waters: Alliance, ACQUITY UPLC (Note: For ultra-high pressure applications, please enquire about customised versions).
• Thermo Fisher: UltiMate 3000, Vanquish series.
• Shimadzu: Prominence, Nexera series.
• Knauer / Metrohm: Full range of ion chromatography systems.

The Challenge with Other Materials:

Proteins, polypeptides, and nucleic acids are extremely sensitive to metal surfaces. When stainless steel columns are used, metal ions can induce protein denaturation or cause non-specific adsorption, resulting in extremely low recovery rates—or even complete experimental failure.

In-Depth Analysis:

PEEK material possesses inherent bio-inertness. It does not chemically react with biological samples, thereby ensuring that the biological activity of the sample remains fully intact from injection through elution.

Value to the Customer:

"You no longer need to worry about your expensive antibody or recombinant protein samples 'going missing' inside the column. Our PEEK hardware ensures that every single microgram of your sample is fully recovered, leading to more reproducible experimental data."

Using Other Materials:

Laboratories frequently handle high-salt buffers (e.g., NaCl). Stainless steel is highly susceptible to corrosion in chloride-rich environments; this not only contaminates the column packing material but can also lead to the complete failure and disposal of the column body.

In-Depth Analysis:

Compared to expensive Hastelloy or Titanium hardware, PEEK offers a more cost-effective, corrosion-free solution. It exhibits no chemical degradation whatsoever, even after prolonged exposure to high-concentration salt solutions.

Value to the Customer:

"A one-time investment for long-term stability. Minimize the need for frequent column replacements caused by corrosion, thereby significantly reducing your laboratory's annual consumables costs."

Using Other Materials:

When analyzing transition metal ions or utilizing strong acidic/basic mobile phases, stainless steel column bodies are prone to microscopic corrosion (pitting). The metal ions released during this process significantly elevate baseline conductivity, thereby masking genuine sample peaks.

In-Depth Analysis:

The inner wall roughness of our PEEK column tubing is precisely controlled to Ra0.2 .

This smooth surface not only minimizes physical adsorption to the column walls but—thanks to PEEK's full pH tolerance (pH 1–14)—also ensures absolutely no ion release, even when exposed to 1.0 M NaOH or strong acidic eluents.

Value to the Customer:

"Achieve a baseline as stable and smooth as a 'mirror surface.' Effectively reduce system noise, enabling lower detection limits (at the ppb level) and sharper peak shapes for your trace analysis applications."